Derek, I'm using MCEBuddy 1.06b10 on Vista, and have a pretty fast machine (E6400 Core2Duo, 2 gigs RAM, ATI x1900xt GPU). I've mainly been converting from DIVX or DVR-MS to iPod 6th Gen compatible, to watch on an iPhone. Transcodes are relatively fast - maybe 15 mins for 30 minutes of video ...